Dustin Bastaich, Ph.D.
Dissertation Title:
Advisor: Bassam Dahman, Ph.D.

Scott Silvey, PhD.
Dissertation Title:
Advisor: Jinze Liu, PhD.

2025

Rasha Alsaadawi, Ph.D.
Dissertation Title: Testing for Conformity with Parametric Distributions Using Level Sets: A Topological Data Analysis Approach
Advisor: Nitai Mukhopadhyay, Ph.D.

Edem Defor, Ph.D.
Dissertation Title: Demystifying Competing Risks in Kidney Transplantation: Scalable Regression, Cluster Informativeness Assessment, and AI-Powered Prediction, With Software
Advisor: Dipankar Bandyopadhyay, Ph.D.

Khoa Le Anh Huynh, Ph.D.
Dissertation Title: A Novel Statistical Learning Framework to Uncover Clinically Significant Spatial Ecotypes with Single Cell Spatial Multiomics Data
Advisor: Jinze Liu, Ph.D.

Ren Rasnick, Ph.D.
Dissertation Title: An Adaptive Method for Covariate Balancing in Block Randomized Clinical Trials
Advisor: Leroy Thacker, Ph.D.

2024

Dongho Shin, Ph.D.
Dissertation Title: Bayesian Estimation of Hierarchical Linear Models with Non-Linear Effects from Incomplete Data
Advisor: Yongyun Shin, Ph.D.

Atika Urmi, Ph.D.
Dissertation Title: Novel Feature Evaluation in Ultra-High Dimensional Right-Censored Data, with Applications to Head and Neck cancer
Advisor: Dipankar Bandyopadhyay, Ph.D.

2023

Joseph Boyle, Ph.D.
Dissertation Title: Estimating Cumulative Spatial Risk Over Time and Extending Mixture Modeling in a Bayesian Framework
Advisor: David Wheeler, Ph.D.

Matthew Carli, Ph.D.
Dissertation Title: Model-based Imputation of Below Detection Limit Missing Data and Group Selection in Bayesian Group Index Regression
Advisor: David Wheeler, Ph.D.

Alicia Richards, Ph.D.
Dissertation Title: Reassessing Replication: Addressing the Replication Crisis from a Statistical Perspective
Advisor: Robert Perera, Ph.D.

Xinxin Sun, Ph.D.
Dissertation Title: Variability in Causal Effects on A Binary Outcome and Noncompliance in A Multisite Randomized Trial
Advisor: Yongyun Shin, Ph.D.

Chen Wang, Ph.D.
Dissertation Title: Early Termination In Phase II Clinical Trials: Admissible Designs Using Decreasingly Informative Priors
Advisor: Roy Sabo, Ph.D.

2022

Martin Lavallee, Ph.D.
Dissertation Title: Estimating Weighted Panel Sizes for Primary Care Providers: An Assessment of Clustering and Novel Methods of Panel Size Estimation on Electronic Medical Records
Advisor: Roy Sabo, Ph.D.

Reuben Retnam, Ph.D.
Dissertation Title: Accelerated Alternating Expectation-Conditional-Maximization Algorithms for fitting Non-Gaussian Observational Longitudinal Data, with Applications to Periodontal Disease
Advisor: Dipankar Bandyopadhyay, Ph.D.

Salem Rustom, Ph.D.
Dissertation Title: Prediction-Based Replacement Algorithms for Response-Adaptive Randomization of Distal Outcomes
Advisor: Robert Perera, Ph.D.

2021

Brielle Forsthoffer, Ph.D.
Dissertation Title: Prognostic Modeling of Recovery Following Stem Cell Transplantation
Advisor: Roy Sabo, Ph.D.

Spiro Stilianoudakis, Ph.D.
Dissertation Title: Methods For Developing A Machine Learning Framework for Precise 3D Domain Boundary Prediction At Base-Level Resolution
Advisor: Mikhail Dozmorov, Ph.D.

Jonathan Yu, Ph.D.
Dissertation Title: Analyzing Electronic Health Records with Time-to-Event Endpoints: Propensity Scores and Semiparametric Approaches
Advisor: Dipankar Bandyopadhyay, Ph.D.

2020

Keighly Bradbrook, Ph.D.
Dissertation Title: Estimating Response Status in Sequential Multiple Assignment (SMAR)-like Trials
Advisor: Roy Sabo, Ph.D.

Erin Donahue, Ph.D.
Dissertation Title: Natural Lead-in Approaches to Response-Adaptive Allocation in Clinical Trials
Advisor: Roy Sabo, Ph.D.

Victoria Garcia, Ph.D.
Dissertation Title: Flexible Methods for Accounting for Distributional Misspecification of the Response-Adaptive Randomization Ratio in Two-Arm Clinical Trials with Continuous or Survival Outcomes
Advisor: Adam Sima, Ph.D.

Paul Hargarten, Ph.D.
Dissertation Title: Accounting for the Uncertainty Due to Chemicals Below the Detection Limit in Mixture Analysis
Advisor: David Wheeler, Ph.D.

Christine Orndahl, Ph.D.
Dissertation Title: Integrated Multiple Adaptive Design Involving Sample Size Re-Estimation and (Covariate-Adjusted) Response-Adaptive Randomization for Continuous and Binary Outcomes
Advisor: Robert Perera, Ph.D.

Viviana Rodriguez, Ph.D.
Dissertation Title: Zero-Inflated Longitudinal Mixture Model for Stochastic Radiographic Lung Compositional Change Following Radiotherapy of Lung Cancer
Advisor: Nitai Mukhopadhyay, Ph.D.

Katherine Stromberg, Ph.D.
Dissertation Title: Adjusting for Dropout in Randomized Controlled Clinical Trials
Advisor: Adam Sima, Ph.D.

2019

Yu Cao, Ph.D.
Dissertation Title: Bayesian Nonparametric Analysis of Longitudinal Data With Non-Ignorable Non-Monotone Missingness
Advisor: Nitai Mukhopadhyay, Ph.D.

Kellen Cresswell, Ph.D.
Dissertation Title: Spectral Methods For the Detection and Characterization of Topologically Associated Domains
Advisor: Mikhail Dozmorov, Ph.D.

Brian Di Pace, Ph.D.
Dissertation Title: Site- and Location-Adjusted Approaches to Adaptive Allocation Clinical Trial Designs
Advisor: Roy Sabo, Ph.D.

Camille Hochheimer, Ph.D.
Dissertation Title: Methods for Evaluating Dropout Attrition in Survey Data
Advisor: Roy Sabo, Ph.D.

Alicia Johns, Ph.D.
Dissertation Title: Methods for Estimating the Optimal Time Lag in Longitudinal Mediation Analysis
Advisor: Robert Perera, Ph.D.

Anny-Claude Joseph, Ph.D.
Dissertation Title: Assessing the Impact of Incorporating Residential Histories into the Spatial Analysis of Cancer Risk
Advisor: David Wheeler, Ph.D.

Jin Liu, Ph.D.
Dissertation Title: Estimating Knots in Bilinear Spline Growth Models with Time-Invariant Covariates In the Framework of Individual Measurement Occasions
Advisor: Robert Perera, Ph.D.

John Stansfield, Ph.D.
Dissertation Title: Methods for Joint Normalization and Comparison of Hi-C data
Advisor: Mikhail Dozmorov, Ph.D.

Keith Zirkle, Ph.D.
Dissertation Title: Estimating Causal Effects in the Presence of Spatial Interference Author
Advisor: David Wheeler, Ph.D.

2018

Amanda Gentry, Ph.D.
Dissertation Title: Penalized Mixed-Effects Ordinal Response Models for High-Dimensional Genomic Data in Twins and Families
Advisor: Nitai Mukhopadhyay, Ph.D.

Jian Kang, Ph.D.
Dissertation Title: Estimating the Respiratory Lung Motion Model Using Tensor Decomposition on Displacement Vector Field
Advisor: Nitai Mukhopadhyay, Ph.D.

Hangcheng Liu, Ph.D.
Dissertation Title: Examining the Confirmatory Tetrad Analysis (CTA) as a Solution of the Inadequacy of Traditional Structural Equation Modeling (SEM) Fit Indices
Advisor: Robert Perera, Ph.D.

2017

Bhanu Evani, Ph.D.
Dissertation Title: Weighted Quantile Sum Regression for Analyzing Correlated Predictors Acting through a Mediation Pathway on a Biological Outcome
Advisor: Robert Perera, Ph.D.

Rebecca Lehman, Ph.D.
Dissertation Title: The Generalized Monotone Incremental Forward Stagewise Method for Modeling Longitudinal, Clustered, and Overdispersed Count Data: Application Predicting Nuclear Bud and Micronuclei Frequencies
Advisor: Nitai Mukhopadhyay, Ph.D.

2016

Jenna Czarnota, Ph.D.
Dissertation Title: Modeling Spatially Varying Effects of Chemical Mixtures
Advisor: David Wheeler, Ph.D.

Kyle Ferber, Ph.D.
Dissertation Title: Methods for Predicting an Ordinal Response with High-Throughput Genomic Data
Advisor: Roy Sabo, Ph.D.

Edmund Glass, Ph.D.
Dissertation Title: Power Analysis in Applied Linear Regression for Cell Type-Specific Differential Expression Detection
Advisor: Mikhail Dozmorov, Ph.D.

Lauren Grant, Ph.D.
Dissertation Title: Selecting Spatial Scale of Area-Level Covariates in Regression Models
Advisor: David Wheeler, Ph.D.

Zirui Gu, Ph.D.
Dissertation Title: Propensity Score for Causal Inference of Multiple and Multivalued Treatments
Advisor: Bassam Dahman, Ph.D.

Kabita Joshi, Ph.D.
Dissertation Title: Finding the Cutpoint of a Continuous Covariate in a Parametric Survival Analysis Model
Advisor: Leroy Thacker, Ph.D.

Aobo Wang, Ph.D.
Dissertation Title: Meta-Analytic Estimation Techniques for Non-Convergent Repeated-Measure Clustered Data
Advisor: Roy Sabo, Ph.D.

Hui Wang, Ph.D.
Dissertation Title: Response Adaptive Randomization using Surrogate and Primary Endpoints
Advisor: Nitai Mukhopadhyay, Ph.D.

Qing Zhou, Ph.D.
Dissertation Title: An Extension of Penalized Ordinal Response Models
Advisor: Kellie Archer, Ph.D.

2015

Hadiza Galadima, Ph.D.
Dissertation Title: Controlling for Confounding when Association is Quantified by Area Under the ROC Curve
Advisor: Donna McClish, Ph.D.

Mateusz Makowski, Ph.D.
Dissertation Title: High-Throughput Data Analysis: Application to Micronuclei Frequency and T-cell Receptor Sequencing
Advisor: Kellie Archer, Ph.D.

Umaporn Siangphoe, Ph.D.
Dissertation Title: Meta-Analysis of Gene Expression Studies
Advisor: Kellie Archer, Ph.D.

2014

Ghalib Bello, Ph.D.
Dissertation Title: Application and Extension of Weighted Quantile Sum Regression for the Development of a Clinical Risk Prediction Tool
Advisor: Chris Gennings, Ph.D.

Naha Farhat, Ph.D.
Dissertation Title: Design and Analysis of Toxicological Experiments with Multiple Endpoints and Synergistic and Inhibitory Effects
Advisor: Leroy Thacker, Ph.D.

Mary Haynes, Ph.D.
Dissertation Title: Incorporating Dependence Boundaries in Simulating Associated Discrete Data
Advisor: Roy Sabo, Ph.D.

Paul Manser, Ph.D.
Dissertation Title: Methods for Integrative Analysis of Genomic Data
Advisor: Mark Reimers, Ph.D.

Chunfeng Ren, Ph.D.
Dissertation Title: Latent Variable Models Given Incompletely Observed Surrogate Outcomes and Covariates
Advisor: Yongyun Shin, Ph.D.

2013

Caroline Carrico, Ph.D.
Dissertation Title: Characterization of a Weighted Quantile Score Approach for Highly Correlated Data in Risk Analysis Scenarios
Advisor: Chris Gennings, Ph.D.

Hanan Hammouri, Ph.D.
Dissertation Title: Review and Extension for the O’Brien Fleming Multiple Testing Procedure
Advisor: Roy Sabo, Ph.D.

Jiayi Hou, Ph.D.
Dissertation Title: Regularization Methods for Predicting an Ordinal Response using Longitudinal High-dimensional Genomic Data
Advisor: Kellie Archer, Ph.D.

Sarah Reese, Ph.D.
Dissertation Title: Detecting and Correcting Batch Effects in High-Throughput Genomic Experiments
Advisor: Kellie Archer, Ph.D.

Emily Sheldon, Ph.D.
Dissertation Title: Choosing the Cut Point for a Restricted Mean in Survival Analysis, a Data Driven Method
Advisor: Leroy Thacker, Ph.D.

Adam Sima, Ph.D.
Dissertation Title: Accounting for Model Uncertainty in Linear Mixed-Effects Models
Advisor: Jessica Ketchum, Ph.D.

Shuxian Sinks, Ph.D.
Dissertation Title: Response Adaptive Design Using Auxiliary and Primary Outcomes
Advisor: Roy Sabo, Ph.D.

Amber Wilk, Ph.D.
Dissertation Title: The Estimation and Evaluation of Optimal Thresholds for Two Sequential Testing Strategies
Advisor: Donna McClish, Ph.D.

2012

Robert Carrico, Ph.D.
Dissertation Title: Unbiased Estimation for the Contextual Effect of Duration of Adolescent Height Growth on Adulthood Obesity and Health Outcomes via Hierarchical Linear and Nonlinear Models
Advisor: Yongyun Shin, Ph.D.

Tobias Guennel, Ph.D.
Dissertation Title: Statistical Methods for Normalization and Analysis of High-Throughput Genomic Data
Advisor: Mark Reimers, Ph.D.

2010

Anwar Ahmed, Ph.D.
Dissertation Title: Cost and Accuracy Comparisons in Medical Testing Using Sequential Testing Strategies
Advisor: Donna McClish, Ph.D.

Maria Capparuccini, Ph.D.
Dissertation Title: Inferential Methods for High-Throughput Methylation Data
Advisor: Kellie Archer, Ph.D.

Tina Cunningham, Ph.D.
Dissertation Title: Power and Sample Size for Three-Level Cluster Designs
Advisor: Robert Johnson, Ph.D.

Epiphanie Nyirabahizi, Ph.D.
Dissertation Title: Bayesian and Frequentist Approaches for the Analysis of Multiple Endpoints Data Resulting from Exposure to Multiple Health Stressors.
Advisor: Chris Gennings, Ph.D.

Andre Williams, Ph.D.
Dissertation Title: Stereotype Logit Models for High Dimensional Data
Advisor: Kellie Archer, Ph.D.

Phillip Yates, Ph.D.
Dissertation Title: An Inferential Framework for Network Hypothesis Tests: With Applications to Biological Networks
Advisor: Nitai Mukhopadhyay, Ph.D.

2009

Bassam Dahman, Ph.D.
Dissertation Title: Nonlinear Models In Multivariate Population Bioequivalence Testing
Advisor: Viswanathan Ramakrishnan, Ph.D.

Rhonda Ellis, Ph.D.
Dissertation Title: Deriving Optimal Composite Scores: Relating Observational/Longitudinal Data with a Primary Endpoint
Advisor: Chris Gennings, Ph.D.

Scott Marshall, Ph.D.
Dissertation Title: An Empirical Approach to Evaluating Sufficient Similarity: Utilization of Euclidean Distance As A Similarity Measure
Advisor: Chris Gennings, Ph.D.

2008

Richard Kennedy, Ph.D.
Dissertation Title: Probe Level Analysis of Affymetrix Microarray Data Author
Advisor: Kellie Archer, Ph.D.

XiangRong Kong, Ph.D.
Dissertation Title: Variable Selection in Competing Risks Using the L1-Penalized Cox Model
Advisor: Kellie Archer, Ph.D.

2007

James Davenport, Ph.D.
Dissertation Title: An Adaptive Dose Finding Design (DOSEFIND) Using A Nonlinear Dose Response Model
Advisor: Viswanathan Ramakrishnan, Ph.D.

2006

Rong Liu, Ph.D.
Dissertation Title: A Comparison for Longitudinal Data Missing Due to Truncation
Advisor: Viswanathan Ramakrishnan, Ph.D.

Jessica McKinney, Ph.D.
Dissertation Title: A Normal-Mixture Model with Random-Effects for RR-Interval Data
Advisor: Viswanathan Ramakrishnan, Ph.D.

Misook Park, Ph.D.
Dissertation Title: Design and Analysis Methods for Cluster Randomized Trials with Pair-Matching on Baseline Outcome: Reduction of Treatment Effect Variance
Advisor: Robert Johnson, Ph.D.

Sharon Yeatts, Ph.D.
Dissertation Title: Statistical Methods and Experimental Design for Inference Regarding Dose and/or Interaction Thresholds Along a Fixed-Ratio Ray
Advisor: Chris Gennings, Ph.D.

Jianmin Zhao, Ph.D.
Dissertation Title: Optimal Clustering: Genetic Constrained K-Means and Linear Programming Algorithms
Advisor: Robert Johnson, Ph.D.

2005

J. Todd Coffey, Ph.D.
Dissertation Title: The Design and Analysis of Experiments with Multiple Types of Outcomes using Nonlinear Threshold Models
Advisor: Chris Gennings, Ph.D.

Heather Hoffman, Ph.D.
Dissertation Title: Maximum Likelihood Estimation of Multivariate Normal Parameters in the Presence of Left-Censored and Missing Values
Advisor: Robert Johnson, Ph.D.

Susan Parker, Ph.D.
Dissertation Title: Solutions to Reduce Problems Associated with Experimental Designs for Nonlinear Models: Conditional Analyses and Penalized Optimal Designs
Advisor: Chris Gennings, Ph.D.

Leanna Stork, Ph.D.
Dissertation Title: A Statistical Equivalence Testing Approach to Testing for Additivity and Determining Sufficiently Similar Mixtures of Many Chemicals Based on Dose-Response
Advisor: Chris Gennings, Ph.D.

2004

Leanne Campbell, Ph.D.
Dissertation Title: Futility Analysis with Covariables
Advisor: Sung Choi, Ph.D.

Adam Hamm, Ph.D.
Dissertation Title: Analysis of an Interaction Threshold in Drug/Chemical Mixtures
Advisor: Hans Carter, Ph.D. & Chris Gennings, Ph.D.

Tammy Massie, Ph.D.
Dissertation Title: Testing Genetic Hypothesis on Bivariate Dichotomous Twin Data Using Repeated Measures Logistic Regression Methodology
Advisor: Viswanathan Ramakrishnan, Ph.D.

Brandy Rutledge, Ph.D.
Dissertation Title: A Comparison of Twin Methods When the Liability is Non-Normal
Advisor: Viswanathan Ramakrishnan, Ph.D.

2003

Michelle Casey, Ph.D.
Dissertation Title: Statistical Methodology for Exploiting the Use of Ray Designs in Studies of Polychemical Mixtures
Advisor: Hans Carter, Ph.D. & Chris Gennings, Ph.D.

Stacey Cofield, Ph.D.
Dissertation Title: Mixed-Effects Models with Variance Groups in R and the Trace Information Criteria (TRIC)
Advisor: Al Best, Ph.D. & Viswanathan Ramakrishnan, Ph.D.

Jeanette Eckel, Ph.D.
Dissertation Title: Statistical Analyses of Time-Course and Dose-Response Microarray Experiments
Advisor: Chris Gennings, Ph.D. & Vernon Chinchilli, Ph.D.

Eric Harvey, Ph.D.
Dissertation Title: Normal Mixture Models for Gene Cluster Identification in Two Dimensional Microarray Data
Advisor: Viswanathan Ramakrishnan, Ph.D.

Leroy Thacker, Ph.D.
Dissertation Title: Influence Diagnostics in the Mixed Linear Model
Advisor: R. K. Elswick, Ph.D.

2002

Lily Ingsrisawang, Ph.D.
Dissertation Title: Mixed Effects Regression Model for Estimating the Effects of Combination Drug Treatments on the Severity of HIV Infection in Persons in Virginia
Advisor: Viswanathan Ramakrishnan, Ph.D. & Elizabeth Turf, Ph.D.

Tristan Massie, Ph.D.
Dissertation Title: Variance Estimation and Influence Functions for Threshold Models
Advisor: Daijin Ko, Ph.D.

2001

Mary Bartholomew, Ph.D.
Dissertation Title: Nonlinear Models with Thresholds for Longitudinal Data
Advisor: Chris Gennings, Ph.D.

Theresa Crofts, Ph.D.
Dissertation Title: Accounting for Treatment by Noise Factor Interactions in Sample Size Determination for the Generalized Linear Mixed Model
Advisor: Russell Boyle, M.S. 

Stephanie Meadows, Ph.D.
Dissertation Title: Optimal Experimental Designs for Detecting Departures from Additivity in Drug/Chemical Mixtures
Advisor: Hans Carter, Ph.D. & Chris Gennings, Ph.D.

Margaret Shih, Ph.D.
Dissertation Title: Titrating and Evaluating Multiple Drug Regimens within Subjects
Advisor: Hans Carter, Ph.D. & Chris Gennings, Ph.D.